Grill Rite Case Study Essay

There are five issues that are relevant.†¨The president’s stance on steady output conflicts with seasonal demand. However, it is unlikely that this will change. The main problem is inventory management. One advantage of having a single, centralized warehouse is the lower need for safety stock due to the canceling effect of random variability in orders from the various regions. Conversely, with separate warehouses, each warehouse needs a relatively larger safety stock to guard against variations in demand. This would enable the centralized warehouse to see what the regional warehouses are stocking and also review their historical demand patterns and future customer forecasts. The fact that the regional warehouses have increased their order size but customer service has not improved reflects that the â€Å"wrong† inventory items are very likely being ordered. Relevant costs would include transaction costs, transportation costs, versus the potential increase in profit by making up a shortage. Other issues include the following: ISSUE ONE: One alternative might be to identify a complementary product that would offset seasonal demand for electric grills. ISSUE TWO: What is needed is overall control of the system that would take into account seasonal variations in demand and achieve a better match between regional demand and supply. This might involve making or improving regional forecasts. In any case, improved system visibility is essential: direct access to regional warehouse data by the main warehouse is needed in order to be able to coordinate and set priorities on inventory shipments to regional warehouses. ISSUE THREE: It is also necessary to examine the feasibility of shipping from one warehouse to another when a shortage occurs. ISSUE FOUR: Develop a policy regarding shipments from the main warehouse (to end user customers versus regional warehouses). ISSUE FIVE: Invest in software (distribution resource planning [DRP]) which would provide desired visibility and also enable the main warehouse manager to â€Å"push† inventory where it is needed versus regional warehouse managers â€Å"pulling† inventory where they believe they need inventory, which may not be correct.

Community Colleges which deliver Essay

Module description: This module covers the importance of volunteerism in contributing to an improvement in the quality of life in communities around UTech and Community Colleges which deliver its programmes as well as the wider society. It further unites classroom instructions with real societal needs and explores the relationship between General Education modules and CSP 1001. MODULE OBJECTIVES: At the end of the module, you should be able to: 1. understand the nature of volunteerism 2. recognize the role of individuals in providing voluntary service 3. appreciate the value of a service ethic in the development of a society. REQUIRED READINGS †¢ Robotham, D. (1998). Vision and Volunteerism. Grace Kennedy Foundation Lecture. †¢ Vision 2030 Jamaica: National Development Plan. National Planning Institute of Jamaica. 2009 ASSESSMENT 1. You will be required to complete four reflective pieces. Each reflection must be type written, Times New Roman, 12pt, double –spaced and no less than one page or more than three pages. You will not be allowed to submit all four pieces at the end of the semester. You must complete each one and submit it on the due date. You will prepare two copies of each assignment. Submit one copy to your lecturer. Have your lecturer sign and date the other copy to acknowledge receipt of your work. Keep all signed copies of your assignments in a safe place. You may need to provide these as evidence of submission of your work. 2. NB: My copy of each reflection is to be e-mailed to mmarch@utech.edu.jm. I do not require a hardcopy of reflections 1 – 3. 3. A hardcopy of your final reflection (REFLECTION # 4) must be submitted to the agency before you leave at the end of the semester. This signed copy of the reflection must be submitted along with the completed timecard. You must present all your work in a folder with the following information on the cover page: NAME: ACADEMIC YEAR: SCHOOL: LECTURER: NAME OF AGENCY/ PROJECT: ID#: SEMESTER: TUTORIAL DAY/TIME: AGENCY SUPERVISOR: 4. At the end of each reflection, you must type this information: Lecturer’s signature: Submission Date: 2 CONTENT Session 1 Week beginning Aug 26 Content Introduction to CSP 1001 †¢ Structure of the module †¢ Assignment to groups and agency †¢ Readings and assignments Activities Assign reading for next class Explain guidelines for reflections ASSIGNMENTS Reflection # 1 2 pages Vision 2030 and community service: a. What does community service/ volunteerism mean to you? b. Which 2 of the 4 goals of Vision 2030 do you think is most closely linked to community service/ volunteerism? Why? c. Select 1 of the 2 goals discussed in (b) and suggest ways you can contribute to achieving this goal through your community service. d. Read Vision and Volunteerism: Reviving Voluntarism in Jamaica, by Don Robotham 2 Week beginning Sept 9 Relating the philosophy and practice of community service / volunteerism to Vision 2030 †¢ What is vision 2030 †¢ Goals of Vision 2030 †¢ Meaning of community service/ volunteerism Reflection # 1 due Discussion of reflection Discuss Vision and Volunteerism. Is volunteerism dead? Can we have a Fifth Peak of volunteerism in Jamaica? Reflection #2 2 pages Identifying your community service project objectives a. Identify your agency and briefly discuss the history, goals and objectives of the agency. b. Bearing the Vision 2030 goal you selected in reflection 1 in mind, identify a set of objectives you aim to fulfill in your assignment at your agency. c. Discuss the specific steps you will take to accomplish those objectives. Reflection # 3 2 pages a. Identify some of the problems/ issues you experienced or witnessed during your placement. b. To what extent did problems you encountered/ witnessed in your placement reflect problems prevalent in the wider Jamaican society? c. What impact do you think these problems will have on our ability to achieve the goals laid out in Vision 2030? d. If the problem was something you encountered, what solution(s) did you employ to address the problem? If the problem was something you witnessed, what possible solutions would you suggest could be used to address the problem? Assignment # 4 3 pages a. Bri efly summarize your impressions of your time spent in your agency. What do you think was the best part of your service? What was the worst part? b. Review the objectives you set for yourself and discuss to what extent were these objectives achieved? c. Discuss in what ways did the community in which you worked benefit from your project. 3 Week beginning Sept 30 Community Service as a change agent †¢ How has community service contributed to our nation’s development historically. †¢ What role can community service play in achieving the goals of Vision 2030. †¢ Reflection # 2 due Discussion of reflection #2 4 Week beginning Oct 28 Community Service for development †¢ Nation †¢ Community †¢ Globally †¢ Role of UTech/ Community Colleges Evaluation of experiences †¢ Challenges †¢ Solutions Reflection # 3 due Discussion of reflection #3 Distribution of evaluation forms. 3 d. State whether the organization would benefit from having more CSP projects completed. Suggest the kind of service which would assist the organization/ community in which you worked, based on your experience there. e. In what ways do you think could CSP 1001 be improved? f. Give reflections on your reading of Vision 2030 and Vision and Volunteerism You will make a copy of this assignment which you will submit to your agency BEFORE YOU LEAVE at the end of the semester. 5 Week beginning Nov 18 Evaluation of experiences †¢ Objectives †¢ Benefits †¢ Challenges †¢ Solutions Reflection # 4 due (Final Assignment)

Agency for Toxic Substances and Disease Registry Essay

Agency for Toxic Substances and Disease Registry The paper "Agency for Toxic Substances and Disease Registry" is a worthy example of an essay on health studiesmedicine.ATDSR is a federal health agency within the United States Department of Health and Human Services. It mainly focuses on reducing public health risks related to exposure to hazardous substances. Its other main objective is to oblige to the public through receptive health actions to enhance safe and healthy environments and thwart unsafe exposures. ATSDR was conceived as a consultative, non-governing agency through the Superfund legislation and began operations in 1985. (American, p.2-34) I would place this agency in the Health and Human Department as it still is because its objectives related to those of the department as a whole. The ATSDR is currently being headed by director Dr. Christopher J. Portier. The director is normally appointed by the president and does not require approval from the Senate. Despite the fact that the agency is an independent functioning bra nch within the Health and Human Services Department, the Centers for Disease Control and Prevention (CDC) carries out most of its administrative duties. The headquarters for the agency is located at Atlanta, Georgia. (American, p.2-34) The roles the agency plays are more than many people think. It advises the Environmental Protection Agency (EPA) and community. It educates doctors and other healthcare professionals concerning the health effects of harmful substances and how to deal with their exposure. It also finances studies on harmful substances. The main problem facing the agency is the lack of knowledge about the hazardous substances among the public. This requires the agency to always endeavor passing or to receive information. The legislature has limited jurisdiction in the operation of the agency. (American, p.2-34) The legislature and the Governor have no direct authority over ATSDR. The activities of the agency will definitely raise interest from different parties. Institu tions that make food for the country must keep up with the developments in the agency. Hospitals and health professionals must also obtain the latest information and training from the agency. The operations of the agency have very important positive effects on the public. They greatly prevent the harm of the public caused by these substances and also offer solutions in the occurrence of these problems. The agency has generally played a vital role in improving the health in the country. (lollar, p.248-250)

Population growth Essay Example | Topics and Well Written Essays - 1000 words

Population growth - Essay Example (high birth rate) (Keyfitz 1-75). THESIS STATEMENT This paper intends to provide a brief idea about the concept of population growth, along with the merits and demerits of this particular aspect in the Canadian context. POPULATION GROWTH IN CANADA This part of the paper will specifically highlight the rate of population growth that has been observed. With the aid of proper analysis it has been noticed that in the year 2011; 33,476,688 people were listed in the census. This particular figure indicated almost twice the figure as compared to the year 1961 and around 10 times higher as compared to the 1861 Census. Between 2006 and 2011, Canada's population has been estimated to take a leap by 5.9%, which was slightly up as compared to the previous period of 2001 to 2006, when it took a leap by 5.4%. Canada's population growth, which was recorded between the years 2006 and 2011 depicted to be highest among all the G8 countries (Canada, France, Germany, Italy, Japan, Russia, United Kingdom , United States and The European Union) which are considered to have the largest economies in the world, as compared to the population growth rate in the previous period i.e. (2001 to 2006). ... However, the rate of Ontario's population growth has been seen to slightly decline during the past five years period to 5.7%, it was recorded as the lowest ever decrease in the level since the period between 1981to1986. Between the years 2006 to 2011, highest rate of population growth in Alberta were located. The growth in population was not only observed by Canada but most provinces met with a leap in the population rate between the years 2006-2011. In the entire metropolitan part along with non-metropolitan areas of Canada, large amount of population growth has been observed. The overall population growth was registered as an increase of 7.4 % in the year 2006 (Canada.gc.ca, â€Å"The Canadian Population in 2011: Population Counts and Growth†). Thus, from the above results, it has been learned that the population growth in Canada has been quite high and similarly other G8 countries also had variable amount of growth rate in terms of Population but Canada seemed to have the h ighest amount as compared to other nations. TRENDS OF POPULATION GROWTH IN THE WORLD The concept of population growth can be argued to pose certain problems in the world economy. With every increase in the birth rate when compared with the decreased death rate, the economy of a particular nation may have to face numerous issues pertaining to economic growth. Mostly less developed countries are likely to be effected with high rate in population growth (Haub, â€Å"Fact Sheet: World Population Trends 2012†). A diagram representing the trends of population growth which shows the possibilities of increase in population by the year 2050 has been cited below: Source: (Haub, â€Å"Fact Sheet: World Population Trends 2012†). Less developed

Research proosal on ASTHMA Proposal Example | Topics and Well Written Essays - 2500 words

Proosal on ASTHMA - Research Proposal Example The descriptive-quantitative research methodology will be adopted using the survey questionnaire as the primary data gathering instrument. Parent – respondents will be selected using purposive sampling and will involve a minimum of 200 respondents determined using post-hoc statistical power analysis. Both descriptive and inferential measures will be utilized in the statistical treatment of the data gathered. SPSS Version 17 will be used in the statistical analysis of data. Introduction Background of the Study The comprehensive health reform legislation known as the Patient Protection and Affordable Care Act (PPACA) of 2010 was signed into law to expand healthcare coverage and cost and enhance the delivery of health care in the United States. Reporting on the feedback from Spanish media, Nix and Adair (2010) articulated that President Barack Obama championed the law to reassure that minorities in the US can avail of access to health care services by way of between coverage opti ons. The PPACA may well one improvement that Mensah and Glover (2007) believe to be possible in the American healthcare setting characterized with a history of pervasive disparities in health status and health care delivery for the last two centuries. Health disparities refer to â€Å"differences in the incidence, prevalence, mortality, and burden of diseases and other adverse health conditions† (National Institutes of Health, as cited in Mensah & Glover, 2007; Pamies & Nsiah-Kumi, 2009). The burden of asthma is an example of disparities in childhood in the US in a general sense (Akinbami & Schoendorf, 2002; Smith, Hatcher-Ross, Wertheimer & Khan, 2005; McDaniel, Paxson & Waldfogel, 2006). While Pamies and Nsiah-Kumi (2009) highlighted the disparities among children of color, Wright and Newman-Giger (2010) focused on Hispanics / Latinos. Of particular concern in this regard is the documented fact that children younger than four years are usually hospitalized because of asthma and that the largest increase in hospitalization trend was among children from 0 to 4 years old (Bigby, 2011; Brooker & Elward, 2010). In the case of children 4 years old and younger, access to healthcare is a matter of parental decision. Compliance and adherence to medication regimen is also largely a parental responsibility. Accordingly, as suggested in Wright and Newman-Giger (2010), there is a need to address how parents’ beliefs and perceptions regarding healthcare play a role in the enhancement of health outcomes of their children, especially those in the 0 to 4 age bracket. Problem Statement As revealed by the Institute of Health (2009), the culture factor in the asthma burden among Hispanic children had been examined from the angle of birth place and lifetime asthma diagnosis, family income and insurance status. Studies have also been undertaken to investigate access to healthcare among cultural minorities from a very general perspective (Edmunds & Coye, 1998; Wright & Newman-Giger, 2010). In the case of asthmatic children four years or younger, however, access to healthcare, as well as compliance and adherence to medical intervention are mediated by their parents or guardians who are mostly relatives. There is a paucity of research which ventured to explore this perspective of disparities in

Analyze and evaluate Robert Frost's The Road Not Taken Essay

Analyze and evaluate Robert Frost's The Road Not Taken - Essay Example According to Larry Finger (1978), he once told an audience, â€Å"You have to be careful of that one; it’s a tricky poem - very tricky† (478) when referring to this poem. The title of the poem is â€Å"The Road Not Taken† rather than â€Å"The Road Less Taken† (emphasis added), which provides the first clue as to the author’s original intentions and a different reading of the poem. Understanding Frost’s background enables one to analyze the poem through each of its four stanzas and trace the linguistic tools used by the author to make his personal philosophical meaning clear. Robert Frost was born in 1874 in San Francisco, California. Although he lived in small apartments throughout the city during his first 11 years, Frost is more commonly associated with the natural scenes of the New England countryside that is used in his poetry (Parini 2000, 3). When his father died, Frost moved with his mother and sister to his paternal grandparents’ home in Massachusetts until his mother found a teaching post in nearby Salem. Life was always a struggle for Frost and his family, but he did well in school and helped on the farm and eventually earned a scholarship to Dartmouth, supplemented by his grandfather, in 1892. Soon after this and before receiving a degree, he returned home to take over his mother’s unruly classroom. He did this and other odd jobs until his secret fiancà © Eleanor graduated from St. Lawrence University and they could get married (Pirini 2000). Frost then began attending Harvard until it became necessary for him to support his gr owing family. His grandfather bought him a farm that Frost attempted to work, but he eventually returned to teaching, through it all demonstrating a heavy preference and talent in the area of literature. However, by this time, his writing was beginning to gain recognition and he was developing his own style and poetic approach. â€Å"The Road Not Taken†

Case study and analysis Example | Topics and Well Written Essays - 250 words

And analysis - Case Study Example Frozen food is also brought in from the kitchen and taken upstairs to the loft where the customers are seated (http://www.rom.on.ca/en/visit-us/shopping-dining/food-studio-caf%C3%A9). On the other hand, c5’s seating arrangement is in a lounge and there are no open spaces to view the kitchen. The lounge is however free from the kitchen noises as it uses a conventional system where the kitchen is far away from the lounge itself. c5 opens from Monday to Sunday between 11am and 3 pm but also has evening services where they have no minimum fee for food and beverages and the charges usually are $1000. According to the Royal Ontario Museum website, both food cafà © and c5 restaurant lounge offer great services including provision of 10% discount to the ROM (Royal Ontario Museum) members (Royal Ontario Museum, n.d., Shopping and Dining). The c5 restaurant lounge website (http://www.c5restaurant.ca/) portrays the restaurant seems as being more elegant and hence will attract highly rated and elegant clients and especially so because of their scenic location (at the pinnacle of the Michael Lee-Chin Crystal with its amazing architecture). It is designed in a lounge manner hence offering privacy, comfort, superb atmosphere most rich and highly classed people normally require and their menu is also on the elegance side (Medicoff, 2007). On the other hand, food cafà © seems to be a food court that is attended by â€Å"the common man† who is mainly in a hurry and does not mind the location, seating arrangement or comfort as long it is convenient enough to grab a quick bite and leave. This is the exact reflection of this cafà © with its open loft space seating around 350 people hence no privacy or comfort, there is noise from the open kitchen and a lot of diners and hence their equipment does not fully serve the pur pose and they may require to expand on their space especially during the peak season where there are many people and less production equipment to serve

EasyJet plc and British Airways Research Paper Example | Topics and Well Written Essays - 1500 words

EasyJet plc and British Airways - Research Paper Example esayJet plc is growing from strength to strength. easyJet plc's working capital position is very strong. BA's stability can be threatened, if there are sudden adverse circumstances like the 9/11. It could find itself unable to meet its current debts if the receivables become uncollectible. Gearing has improved in BA by 23.5pp. However, easyJet has resorted to borrowing to fund the capital expenditure. However, the key operating data in BA are encouraging and will appear to provide a firm footing to lift itself out of this prevailing troubled circumstances. Despite the current circumstances, BA is continuing to invest in operating assets to improve its value-added services, which it considers to be the backbone and introducing cost reduction schemes to minimize the financial burden arising from the magnitude of operating expenses. The improvements as seen on the operating data are welcome news to the Senior Management at BA. If the trend continues BA will be on its way to the financial recovery. easyJet plc Consolidated financial and operating data Year ended 30 September Change (unaudited) 2006 2005 % Key performance indicators Return on equity (1) 10.1% 7.1% 3.0pp Profit before tax per seat () (2) 3.32 2.38 39.6 Revenue per seat () (3) 41.66 38.66 7.8 Cost per seat () (4) 38.34 36.28 5.7 Cost per seat excluding fuel () (5) 28.36 28.78 (1.5) Seats flown (millions) (6) 38.9 34.7 12.1 (http://academia-research.com/files/message/603169_EasyJet%20annual_report_2006.pdf) British Airways 2005-06 2004-05 Group results Revenue m up 9.6% 8,515 7,772 Operating profit m up 26.8% 705 556 Profit before tax m up 20.9% 620 513 Attributable profit for the year m up 19.6% 451 377 Net assets m up 48.5%...It could find itself unable to meet its current debts if the receivables become uncollectible. Despite the current circumstances, BA is continuing to invest in operating assets to improve its value-added services, which it considers to be the backbone and introducing cost reduction schemes to minimize the financial burden arising from the magnitude of operating expenses. The Core competence of easyJet plc is the winning combination of 'low cost with care and convenience'. Low cost is by far the most important component. Convenience is not only about their award winning website but also the network of centrally located airports, which give their customers quick access to where they want to go. The Core competence of BA is in being an Internet age airline with online systems and features that make the travel experience simple and hassle free. Providing superb customer service and products, which their customers want is at the heart of our business. The main activities of the Company and its subsidiaries are the operation of international and domestic scheduled and charter air services for the carriage of passengers, freight and mail and the provision of ancillary services. The key achievements of easyJet plc have been given prominence, cleverly projecting and differentiating itself and gaining mileage in image building.

Cyber Security Industry Research Paper Example | Topics and Well Written Essays - 3500 words

Cyber Security Industry - Research Paper Example is initiating its business that can provide the customers with a safer IT working environment. The thesis paper has enlightened the areas such as business overview, marketing, human resource, and financial information explicitly and comprehensively that one needs to consider for the start-up of a business. By looking at the market trends of the growing businesses, it has come to notice that cyber security industry is one of the sectors that are growing at an unprecedented rate due to the technological advancement (Gallaher, Link & Rowe, pp. 89-94). In this regard, the enterprise ABC Corporation Ltd. intends to initiate the business in the cyber security industry. The primary business unit of the company is located in the downtown area of Atlanta, Georgia. This is because it is one of the industrial hubs with proximity to customers. ABC Corporation is initiating its business operation from a local platform; however, the future strategy includes business growth and expansion over the entire market of United States in the industry of cyber security and on international market as well. The startup business would analyze the potential clients system, test it for vulnerabilities of a hacker, and provide solutions to resolving those vulnerabilities, and improving the overall security of the information. Primary products and services offered by ABC Corporation to its clients include cyber security assessments, vulnerability analysis, cyber security audits, cyber security training, secure broadband network communications, cyber intelligence systems, software and analytics to address cyberspace threats, and other capabilities that enable the customers to detect, evaluate and respond to cyber threats (Gallaher, Link & Rowe, pp. 89-94). Upon the start-up of the business in the sector of cyber security, ABC Corporation would require furniture and fixtures, office equipments such as computer systems with database server, network security that include computer

Saving Belizes Barrier Reefs Essay Example for Free

Saving Belizes Barrier Reefs Essay Earth’s resources are not limitless, they have breaking points and natural properties can be threatened by a multitude of factors that can leave the area in ruins. The Belize Barrier Reef is such an area. It is a breathtaking natural system, home to a diverse array of life forms, which is being threatened by mankind and environmental factors. Conservation efforts can be put into action to ensure the continued existence of this site, but those efforts require financial backing. With proper monetary support, the increased conservation efforts can reverse the destruction on the reef. The Belize Barrier Reef Reserve System is a rich and diverse ecosystem that can be preserved for the enjoyment of generations to come. * The coastal area of Belize is the location of The Belize Barrier Reef Reserve System. The reef is the largest of its kind within the northern hemisphere, stretching out over 200 miles along Belize’s coast. The reef contains many mangrove forests, large atolls, pristine lagoons, and approximately 450 sand cays. Additionally, the reef is home to a plethora of marine life which both directly and indirectly impacts this ecosystem and the diverse life contained within. The preservation of this site is crucial due to the abundant threatened species that make their home in the reef. Specifically, there are nearly a thousand species that inhabit the reef such as the loggerhead, green, and hawksbill sea turtles, the largest population of manatees in the world, and the American marine crocodile. Additionally, the reef system is home to numerous types of coral, sharks, barracuda, dolphins, angelfish, and several species of birds. The aquatic and plant life of the reef react and prosper through their connections; the reef and the vegetation within provide shelter and food for this array of life that live within (UNESCO World Heritage Centre, 1992-2012). * With the abundant life forms that exist within the reef, it is imperative that it be protected, yet the reef system is in danger as a result of huma n interference and climate issues. Because the world is a giant ecosystem, human mistreatment has led to imbalances on a dramatic level, such as fluctuating climate. This climate control issue is adversely affecting both  the water level in the reef and the organisms within. Tropical storms have been an issue as well as they threaten the coast with tidal waves and erosion, however the reef and mangrove cays do offer significant protection to the areas further inland (Young, 2008). According to World Resources Institute (2008), â€Å"Coral reefs and mangroves are highly interconnected habitats, physically supporting each other and providing habitat for many species. For example, mangroves filter sediment and pollutants from coastal runoff, supporting the clean water favored by corals. Many species important to fisheries and tourism rely upon mangrove habitat for part of their life-cycle† (p. 2). * With the delicate balance of this ecosystem and all it offers, it would stand to reason that locals would do everything possible to preserve the reef, yet that is not the case. In fact, locals and tourists are threatening this precious ecosystem and could cause its decline. Deforestation, oil drilling, and coastal development are all threats. In 2002 crude oil was discovered in Belize, igniting frenzy and attracting hundreds of prospectors. Additionally, the growing population and tourism industry has led to rapid development for both residential and commercial purposes (Young, 2008). â€Å"Over the last five decades, large-scale agriculture (citrus, bananas, sugar cane) and, more recently, large-scale aquaculture (shrimp and tilapia farming) have escalated at the expense of the forests. Coupled with rapid and increasing coastal development, illegal logging, and slash-and-burn agriculture, Belize is currently experiencing a deforestation rate that is twice that of Central America (2.3% vs. 1.2% annually)†¦Ã¢â‚¬  (Young, 2008, para. 4). * Fortunately, others have realized the value of the reef system and have taken steps to protect it. â€Å"The preservation of the Belize Barrier Reef Reserve System is critical to both its marine inhabitants and the local communities that depend on the site for their livelihoods† (Terracurve, 2009, para. 3). In 2009, the United Nation Educational, Scientific, and Cultural Organization (UNESCO) added the reef reserve system to their list of World Heritage in Danger sites. The UNESCO foundation hopes to spread the message that the Belize Reef System belongs to all people and its natural heritage and beauty should be protected (UNESCO World Heritage Centre, 1992-2012). Conservation efforts have also been put into play to ensure this world heritage sites continued existence. The department of fishery in Belize has recognized the need to reform the  national fisheries policy in an effort to control over fishing in the reefs, which is a substantial threat to the reef. Such reforms should help the over fished areas to rebuild, offer protection to the reefs and delicate coral, and add to the number of protected marine areas where fishing is not allowed (Wildlife Conservation Society, 2012). Conservation efforts for the Barrier Reef system still have a long way to go. Local Belize communities and their inhabitants are one group that can do much good towards the conservation of this national treasure. However, in order for this to happen the locals need to be educated on conservation and its benefits and become invested in the reefs. Although this is a challenge do to the extreme poverty that exists within Belize and the citizens’ access to educational information. Poverty greatly increases the instances of environmental misuse because those affected typically have greater worries than environmental conservation. In order to implement a conservation plan that includes involvement from local citizens, there must also be efforts made to boost the socio-economic standing of the citizens. Long term preservation of the reef could be financially beneficial to the Belize economy and better the citizen’s socio-economic standings. Additionally, allowing the citizens to work with the government officials towards making decisions concerning the reef will give them a sense of investment in the reef (Young, 2008). * Improving the socio-economic conditions in Belize and educating citizens is just a small step that can lead to more effective conservation efforts for the reef. That still leaves the issues of outside interference on the ecosystem such as oil drilling and deforestation. Although Belize has established a protection plan for certain land a sea areas, it is apparent that tighter restrictions are needed. In particular, oil drilling and deforestation are major issues that threaten the reef that should have increased restrictions placed on them. This will require increased monitoring and amendments to the protected area systems. Additionally, the three management teams which oversee the protected areas appear to all have different ideas concerning best conservation practices. For that reason it would make sense to unify the groups, leaving only one division to oversee the protected areas and enforce regulations (Meerman, 2004). Drastic measures to preserve the reef system need to be taken now, before it is too late. If conservation efforts are not increased, coral health and fish  populations will continue to decline and the mangrove cays will face extinction. As it stands, the shark population in the reef waters has already declined, which is an indicator as to the reefs health. The absence of sharks in the reefs allows the populations of barracudas and rays to increase and take control. These second rate predators can have damaging effects on the reefs if there numbers are not controlled, such as limiting the populations of parrot fish, conch, and lobster. Lobster is important in Belize as it is one of t he country’s major exports. Parrot fish play an integral role in the reef as well, they are plant eaters and there food source is algae. Without parrot fish and other plant eating fish eating the algae and keeping it in check, it will spread until the reef is consumed by it, which could be irreversible (Kryt Ward, 2008). The Barrier Reef Reserve System off of the coast of Belize is breathtaking example of nature’s beauty. Additionally, it is a precious natural system teaming with diverse life forms. Although climate and human interference have caused the reef to become an endangered site, it is not too late to reverse the effects of mistreatment. Education on conservation efforts and increased restrictions can greatly increase the reefs chances of survival for generations to come. Without these efforts, a precious natural resource will be lost, and the reef is most certainly worth preserving. References * Kryt, K. Ward, J. (2008). Trouble in paradise-the struggle to save Belize’s Glover’s atoll. Retrieved from http://www.earthisland.org/journal/index.php/eij/article/trouble_in_paradise/ Meerman, J.C. (2004). Protected Areas Policy and System Plan: Protected Area System Assessment Analysis. Retrieved from http://biological-diversity.info/NPAPSP.htm * Terracurve. (2009). Help protect the Belize Barrier Reef with the support of the United Nations. Retrieved from http://www.terracurve.com/2009/07/01/help-protect-the-belize-barrier-reef-with-the-support-of-the-united-nations/ * UNESCO World Heritage Centre. (1992-2012). Belize Barrier Reef Reserve System. Retrieved from http://whc.unesco.org/en/list/764 Wildlife Conservation Society. (2012).

Drug Discovery and Development Processes

Drug Discovery and Development Processes INTRODUCTION The human body is a miracle but it is also extremely vulnerable. Many illnesses and disorders are still untreatable. Fortunately science is always evolving. It is unravelling more and more secrets about how our body works and which process is occurring in conditions of sickness or health. The challenge is to use our scientific knowledge to discover new, innovative drugs, a new hope for the patients all over the world. Drug Designing or Drug Discovery and Development is an inventive process of finding new medications based on understanding of the biological target. Vast majority of drugs are small molecules designed to bind, interact and modulate the activity of specific biological proteins. These proteins which may also be receptors bind to and interact with other molecules to perform the numerous functions required for the maintenance of life. In many illnesses, one or more proteins or receptors in the body are not working correctly. That is what the scientists try to detect. If they discover which proteins or receptors cause an illness then these same proteins become the target for the development of a new drug. Thus, the target is the naturally existing cellular or molecular structure involved in the pathology of interest that the drug-in-development is meant to act on. Drugs work by interacting with target molecules (receptors) in our bodies and altering their activities in a way that is benef icial to our health. In some cases, the effect of a drug is to stimulate the activity of its targets (an agonist) while in other cases the drug blocks the activity of its target (an antagonist). DRUG DISCOVERY PROGRAMME A drug discovery programme initiates because of a disease or a clinical condition for which a suitable medical product is not available. It is this unmet clinical need which is the underlying driving motivation for the project. Developing a drug from an original idea to the launch of the finished product is a very labor-intensive, time consuming and expensive procedure which can take over 14 years to complete. Target-based drug discovery starts with a thorough understanding of the disease mechanism and the role of enzymes, receptors or proteins within the disease pathology. The initial research would include experimental procedures to identify proteins responsible of the disease and generation a hypothesis that the inhibition or activation of those protein or pathway will result in a therapeutic effect in a disease state. The outcome is the selection of a target which may require further validation prior to progression into the lead discovery phase in order to justify a drug discovery effort. During lead discovery an intensive search ensues with the help of a technique called High Throughput Screening (HTS) to find a drug-like molecule or biological therapeutic, typically termed as a development candidate, that will progress into the preclinical, and if successful, into clinical development and ultimately be a marketed medicine. Drug discovery process from target identification and validation through to filing of a compound and the approximate timescale for these processes. FDA: Food and Drug Administration; IND: Investigational New Drug; NDA: New Drug Application. DRUG TARGETS One of the most important steps in developing a new drug is target identification and validation. A target is a broad term which can be applied to a range of biological entities such as proteins, genes and RNA. A drug target is a key molecule involved in a particular metabolic or signal transduction pathway that is specific to a disease condition or a specific disease. Knowing the cellular targets of drugs is crucial if the process of drug discovery is to be made more efficient. Identifying the full spectrum of targets associated with a bioactive small molecule can lead to faster optimization, understanding of off-target side effects and the ability to minimize possible toxicities early on in the process. It is vital to have as much evidence as possible to support a target of choice before investing more resources in the target. Good targets share several features: involvement in a crucial biological pathway; distinction from any previously known target; functionally and structurally characterized; and druggable. A ‘druggable’ target is accessible to the putative drug molecule and upon binding elicits a biological response which can be measured both in vitro and in vivo. It also needs to be efficacious, safe, meet clinical and commercial needs. When searching for novel drug targets, candidates can be assessed according to how many of these features they have, as well as participation in a biological process critical to the disease. Identification of the target is followed by its validation which a process of physiologically, pathologically and pharmacologically evaluating a biomolecule. It might be performed at the molecular, cellular or whole animal level. The potential drug target is then subject to high-throughput screening against a library of drug-like compounds or to rational drug designin g. However, the term ‘drug target’ itself has several limitations. The following points should be kept in mind: First, a drug is disease-dependent, that is, every target is involved in a spectrum of diseases. Second, most human diseases are rather complicated and involve a number of risk factors, so there clearly are many different targets with respect to a specific disease. Targeting a specific target could not conceivably cure a disease. Third, there are many drugs targets the same target and one drug may have more than one target. The relationship between a drug and its target is not one-to-one but many-to-one. According to whether there are drugs available, a drug target can be classified into two classes: established drug targets and potential drug targets. The former are those for which there a good scientific understanding, supported by a lengthy publication history regarding both how the target functions in normal physiology and how it is involved in human pathology. Furthermore, there are many drugs targeting this target. The latter are those biomolecules whose functions are not fully understood and which lack drugs targeting them. Potential targets suggest directions for complete new drug research. At present, the most frequent protein targets for which successful drugs have been developed include proteases, kinases, GPCRs and nuclear hormone receptors. GPCRs and enzymes represent the most important classes of proteins for drug discovery. According to the DrugBank database, there are 435 effect-mediating drug targets in human genome. These structures are targets of 989 unique drugs, through 2,242 drug-target interactions. The dataset shows that receptors make up the largest group of drug targets: 193 proteins (44%) of the human drug targets) are receptors, and 82 (19%) of these are G protein-coupled receptors (GPCRs). In overall dataset, ~36% of drug targets are GPCRs. Ligand-gated ion channels are second largest receptor target class followed by receptor tyrosine kinases at the third place. Enzymes are the second largest group of target proteins in the human genome, comprising 29% of all human drug targets. Hydrolases are the most common class of enzymatic drug targets, comprising 49% of all human enzyme drug targets followed by oxidoreductases and transferases comprising 27% and 19% respectively. In addition, the majority (78%) of the enzyme targets are soluble proteins and not membrane-associated proteins. E.g.; cyclooxygenase 1 and cyclooxygenase 2, which belong to the oxidoreductase family are targeted by acetylsalicylic acid (aspirin).

Race and Social Class :: essays research papers

â€Å"I can’t help it, that I am Black.† â€Å"Why can’t people except me the way I am?† â€Å"Do you want me to go hang myself?† Surprised that someone would say this things still in this century, well don’t be because race will always be there. These are the things that were said by a floor mate of mine name Shelly. She is so nice but she is always upset because this guy name Mike makes remarks about her and she can’t say or do anything to change how he feels. She got drunk last night and she said everything that was on her mind to Mike and all he did was walk away. The reason I told you about Shelly because she is only one of those many people who go through torcher from other people. I thought that what Mike was doing to Shelly was unfair because she and her family has worked so hard to be where they are today. To my knowledge, Shelly’s parents are probably middle class and are fitting in the society. On the other hand, Mik e’s parents are in high class level and I think that is why he is the way he is towards Blacks. He once told me that he has never lived in the same area as a Black family.   Ã‚  Ã‚  Ã‚  Ã‚  William Julius Wilson determines life chances and the important factors of social class. He is a Black man from Harvard University. He wrote a book called â€Å"Declining Significance of Race†. Wilson has many arguments, he argues that the city has low skilled people with low income, while the suburbs has more high class opportunity and so the suburbs have more high class people. He also argues that addressing the needs of the underclass cannot be based only on race, instead he says â€Å" it’s quite clear to me that we’re going to have to revise discussion of the need for WPA style jobs. Only these more structurally based programs, open to all in need, are likely to garner political support among the majority and to address the deep-seated problems that changes in the global economy have wrought†(Time, June 17, 1996:57).

Poor Qulity in the Home Construction Market :: Residential Housing Real Estate

With low finance rates more Americans are purchasing homes than ever before, but the quality of these mass constructed homes is dropping. Imagine breaking your back for ten years to save up for your first home and losing it all and more because your home fell victim to a fire. This is a common example of what may happen when a house is poorly constructed. Home builders are disregarding the much needed safety regulations when calculating their budgets. In the construction business time is money, and when time is an issue sacrifices are often made. It is these sacrifices that are lowering the standards of building within the home-building industry, costing Americans millions annually due to property losses and repair costs. Foundations are cracking due to poor engineering and rushed pouring processes, and homes are burning as if they were mere piles of kindling due to faulty wiring and the disregard of general fire precaution. A problem that has become increasingly more prevalent the l ast couple of years is the loss of property due to natural disasters. Regulations and guidelines have been developed and introduced into the construction industry to aid in preventing the destruction of homes in such a crisis. The devastation these natural disasters may cause accounts for billions annually but can drastically be reduced with stricter enforcement of precautionary measures outlined in construction regulation codes. Who should be held accountable? Maybe we should penalize the construction companies for ignoring what may seem like insignificant precautionary measures in order to complete projects on time and within budget. Or should we turn to the bigger picture and question the state or national level regulation agencies for their slacking enforcement and infrequent development of these imperative regulatory codes? Where ever the problem originates from, it needs to be resolved before the appeal of being an American homeowner loses its prestige. More importantly, homeo wners are at a financial and physical risk because safety and quality control has lost its priority. Purchasing a home is many times one of the most important investments a person or family may encounter. Most commonly homes are financed over periods ranging from ten to twenty years, but in some cases this is ample time for the integrity of poorly constructed homes to deteriorate beyond repair. This raises much concern within state regulatory agencies that overlook the lacking quality in thousands of homes built annually. Agencies such as the Texas Department of Regulation and Licensing and OSHA provide strict guidelines covering many different aspects of construction in order to insure quality and safety throughout the industry.

Double Vision :: Personal Narrative Writing

Double Vision We met at Astor Place. I said hello, she said hi. Her face was the same as I remembered. It was a Sunday afternoon in autumn, and the wind made her cheeks rosy. She smiled curiously. Looking back, maybe it was less the wind and more the circumstances. It had been quite sometime since our last encounter, two months, if my memory served me. â€Å"Shall we,† I said leading the way. Down the stairs of the subway station we passed through the turnstile, I first, then she. Subway’s no way for a good man to go down, rich man won’t ride and the hobo he can drown. Waiting for the 6 train I began to fidget, as Elton John’s lyrics bounced back and forth in my mind. She attempted to talk over the roar of the uptown train. â€Å"How was your summer?† she loudly inquired. And I thank the lord â€Å"Is that what you really want to ask?† I shouted back. for the people I have found. She turned her head and nodded, as the train rolled to a stop. The doors opened and the people poured out, filling the platform. Her body backed into mine, and a faint, familiar fragrance swept through me. Time stood as the aroma lingered. A heartbeat later we were fighting our way through the entanglement. Entering the passenger car, we managed to find an empty seat. The smell of her hair. I remembered that, I remembered the morning after finding my face softly nestled in a pillow of blonde, breathing her in. She had yet to wake, and the sun rising through her barred apartment windows painted crisscrossing patterns on her exposed back. â€Å"14TH STREETUNION SQUARE. THIS IS A BRONX BOUND 6 TRAIN, NEXT STOP 23RD STREET.† The mechanical voice stole me back to the present. Gathering myself I apologized to her. â€Å"Whatever for?† she asked. â€Å"I’m not quite myself today, I, um, I seem to have lost my words†¦Ã¢â‚¬  I trailed off watching the child in the seat across from me wriggle in the arms of his mother, fighting for his freedom, the mother’s face a picture of exhaustion. â€Å"Don’t give it a second thought, sometimes it’s nice to be alone, alone with someone else,† she said. Through the reflection in the window in front of me, I stole a glance at her face as she spoke those last words.

Critique of the play Hamlet Essay

The Theatrical Play Hamlet was a story about a man name Hamlet who meets a ghost who â€Å"apparently† was his father, and tells hamlet to seek revenge for his murder from his brother who was Hamlets Uncle that married his mother. Hamlet love affair sees him insane, but does not now it is fake, later becoming insane killing herself after Hamlet kills her father. The brother and son seek revenge for his family’s death and duals with Hamlet getting himself killed with a poisoned sword. The king tries to poison Hamlet, but his wife drinks the poison and dies. Hamlet then proceed to kill Claudius, getting poisoned by the dual sword and dying, ending the play with the royal family dead. To make this story interesting the production group used different elements to help make the audience engaged; the main elements presented were lighting, scenery and entertainment. The lighting in the play Hamlet was for the audience to focus on particular images; it was also used for coordin ation with the actor and music. The key element in lighting was colour. An example in the play demonstrating change in mood due to lighting was, when the ghost appears on stage the light would start to flicker to show lightning, this could be to bring fear, or seriousness. Special effects of the lighting were also shown during the soliloquies so the artist can stand out from the background to draw attention to itself from the focus and connection with audience; this was shown by the light only reflecting on the artist. Another element that helped make the play good was the scenery. Each theater is different from its own way especially through the sizes of each stage. Even though the stage was small at the theater attended, the production group did a wonderful job of using the whole space with different objects to make the stage seem alive and big. Some objects were constantly used to make the setting of particular scenes; an example of this was the wood table that had been made into a bed or a dresser to show a room, a grave for Old Hamlet, a dinner table, and a stage for the Players. Objects were used for setting and visual purposes of clues to prepare the audience for the upcoming scenes. The production group also used the sound/music/dance in the form of entertainment. When a certain character used dance or songs in their performance, it was shown as insanity or an abnormal behavior. The entertainments were used to engage audience and to help them comprehend different emotions. During the play there were few missing scenes such as, the spy that was sent by Polonius for his son  Laertes, which held no importance for the group to reenact. Another scene that was missing was all of the Fortinbras scenes. The reason taken out was due to memorizing extra lines and no effect to the play if it were to not be presented; but by not including this scene the ending was a gray area of not knowing what happens to the throne after all the royals death. The production group had done a wonderful job in the play Hamlet that was about the betrayal of a brother, the revenge for a father, the love and marriage for two people, and the deaths of the guilty and innocent. The theatrical play demonstrated its performance through different elements; the three most important element included lighting, scenery, and entertainment of sound, music, and dance. Even though there was a slight gray area of the missing scene of Fortinbras, the performance itself was unique and amazing to watch.

Assess the importance of the Celtic Iron Age regarding

The Iron Age was crucial as it was the development of highly sophisticated social and physiological development of humans'. There are multiple reasons why the Celtic Iron age has such significant. Firstly, the technology that had been created by the new found metal had major impacted on the Celtic society. Secondly, new lifestyles that massively change how humans use to live. Amongst this coinage had also been Introduced within Celtic regions which Invented more practical ways of trading. There was also an Increase interest In personal appearance along with a more relaxed lifestyle.Celtic people also began to Invent things to do for leisure. Lastly, Celtic religion started to evolve and politics was beginning to be invented. The Celtic Iron Age would be considered the most important within the Three-age System regarding to human societal development in Europe. It has made many improvements for humans to achieve the level of societal complexity today. The development of advance human society has mostly evolved though the revolutionary advances in weapons and crafts that were forged by Iron. Iron was very significant and made life for humans much easier after its discovery.Many of the weapons forged by iron was much stronger and lighter Han bronze, this allowed for improvements to be made to weapons and agricultural tools. Many of the common tools that were used during the Celtic Iron Age are till used today. For example the sickles or pruning hooks which were used by Iron Age farmers, the tool was used for cutting and shaping branches and hurdles unlike most farmers that use them today as to harvest cereal crops or cutting grass for hay. There were also several other tools that were developed during the Iron Age and its designs have been kept and improved on for many years.Tools such as the hammers, files, axes and many other metal-working tools. Even though early stages of these tools have already been developed during the Stone and Bronze Age, the Celtic Iron Age has truly perfect it. Evidence form everyday tools that society still uses in the 20th century shows many similarities and some can be considered virtually identical to the tools that were used more than two thousand years ago. The tools were made to build houses, make weapons and farm. These were the necessary tools to that develop human society Into a more complex one.Thus, this demonstrates that the Celtic Iron Age In Europe has help significantly to the development of human society s the discovery of Iron was revolutionary wealth humans. Without this ore, modern society In Europe would have not reach Its level of sophistication as Iron played a also shown impressive improvements that are still useful to everyday life in modern society. Therefore this shows how the Celtic Iron age has a high level of importance regarding to societal development in Europe. 1 Oliver, N. 2011. A History of Ancient Brittany.United Kingdom, Phoenix. Up. 217 2 Ibid. , 3 S. James and V. Rugby, †˜Iron Farming Tools', British Museum [weapon], (1997) http:// www. Brutishness. Org/explore/highlights/highlight_bob]sects/pee_BRB/I/ Ron_farming_tools. Asps Para. 3, accessed 27 June 2013. The importance of the Celtic Iron age regarding to human societal development in Europe was significant as the development and improvements of agriculture had greatly affected the way that people had lived in the in the past ages. It has also have shaped how humans tend to live today.The Stone Age and the Bronze Age had consisted of hunting and gathering food and there was little to no agricultural activity. However, the Celtic Iron Age was primarily agricultural and their daily routines would have consisted with maintaining crops and livestock. This can be seen though evidence in the environment. Evidence in forms of carbonized grains and pollen, it was shown that new crops were introduced and many wheat's had been farmed and grown in the fields. This meant that people began to develop permanen t settlement as they were preoccupied by farming and caring for livestock.As humans began to stay in permanent housing they also began to live in villages. This was unlike the previous ages as they were mostly hunter-gather societies when it was rarely done. They would only hunt in small groups and constantly travel as there were high risk of danger. The new agricultural life style opened many opportunities of improvement to the human society. Living in villages increase and improved human social development as they gain new skills through looking after life stock and farming as this improved their intelligence.As historian, a Neil Oliver quotes, ‘These steps alone had made a profound and deeply transforming social revolution's. The Iron Age did not Just improve human society by advancing in technology, however, they have also improved on having a better grasp on the practical necessities such social and leisure activities. During the Celtic Iron Age, the Celtic had much more time than their ancestors after the development of permanent housing. They were able to socialism more and focus on things that they were not able to in the past.This included on their personal appearances and activities for leisure. Archaeological evidence of Celtic Iron Age housing shows that many of these houses contained looms. Evidence of clothing form the Celtic Iron Age have shown to be made out of either linen or wool. The fabric would have been dyed bright colors and were woven with striped or checked patterns. There was also evidence from the archaeological record of brooches, pins and other dress accessories that would have played both a functional and decorative role on the clothing.Classical text also gives clues of what the Cells may have looked like an example of this is Odorous Sculls who was an Ancient Greek Historian, who wrote: When they are eating the moustache becomes entangled in the food, and when they that both men and women may have grown their hair long and also plaited it. This evidence has truly shown how human society had changed after the Iron Age. It demonstrates how humans have developed in intelligence by domesticating animals and also on how they have evolved.Thus, the importance of the Celtic Iron Age regarding to societal development is very significant as this had not only taught them a more relaxing way of life. It was also the first steps of humans being more social and advance creatures though their physiological development. Being able to maintain livestock, farm and also create accessories and tools that were much more developed than previous ages. 4 Jinni. S. , ‘Ancient History in depth: Life in an Iron Age Village', BBC History [weapon], (2013) http://www. BBC. O. UK/history/ancient/British_prehistory/ orange_intro_01 . SHTML Agriculture Para. , accessed 4 July 2013. Upriver, pop. Cit. , p. 217 6 Jinni, pop. Cit,. Appearance Para. 2 accessed 4 July 2013. Fernando. C. , ‘Pair of metal detector friends disc over three quarters of a ton of Iron Age coins worth Loom buried in a field in Jersey after searching for 30 years', Mainline [weapon}, (2012) http://www. Dilemma. Co. UK/sciences/article-2164897/ Iron-Age-coins-worth-l Mom-discovered-]erase-metal-detector-friends. HTML accessed 6 July Lastly, the importance of the Celtic Iron age regarding to human societal development in Europe is significant as the religions and rules that existed during he time has truly effected on how society is run in the present. The Celtic Iron Age demonstrated that religion had a large impact in Celtic society much like it has in modern society. The Cells shared a common religious system, it also revealed that the Cells had strict rules of worship to their religion as evidence of human sacrifices such as the Tolland Man and Windy Girl have been found.The Greek and Roman texts provide a number of pertinent observations and a comprehensive account was given by Caesar in his description of Goulash society. Th e largest religion in modern society had also came out of the Celtic Iron Age. The Monastery of Illuminant Afar also known as the Illuminant Major can be considered the axis of early Celtic Christianity. Evidence of this includes the ruins of churches that are in modern Ireland and Britain. Many Celtic Scripps and illustrations have also suggest that Christianity has emerged from the era.This also wildly demonstrates how important the Celtic Iron Age is to the development of human society as without it, many things in modern society may not have existed. Political control and early stages of feudalism was also introduced as in each city state or village. In each village there would be an en or lord', legal or ‘king' and ins or ‘governor-priest' controlling it. This example demonstrates a high level of human intelligence and also an example of how the Iron Age was very significant regarding to humans societal development as this system last for centuries which demonstrate d its success.Another significant introduction was the introduction of coins within Europe. This demonstrated a large change in how humans were now living. Through coins, it was positive that trading had become a popular lifestyle, by having coins, the Cells were beginning to have an easier life style as they didn't need to trade in the crops that they grow. They were able to grow more food and grow wealthy. As this system of exchanging money for goods is still the impact it has on the development of human society, as from the Iron Age many new systems have developed.Which demonstrates how significant the Celtic Iron Age really is as many things may not exist if the Iron Age had not occur. Thus, the Celtic Iron Age was highly significant to human societal development in Europe. The Iron Age had introduced a number of complex things that enabled human intelligence to expand. This included farming, new tools, religion, politics and the adaptation of a new epistyle. The Celtic Iron Age had truly changed how humans have lived and improved.

ECCB & Property Development in Malaysia Essay

Marketers are either directly or indirectly involved in the efforts to promote environmentally conscious behavior amongst the consumers with a view to addressing the global concerns about the global warming (Rauschelbach, 2002). Governments have come up with various policies on climate change that companies and corporations, both national and multinational, must comply with. Consumers in Malaysia and other countries have started being environment conscious by consuming environmentally friendly products (Woolley & Kimmins). The environmentally conscious consumer behavior is a way the consumers ensure that environment around them is preserved, especially in view of escalating challenges of garbage disposal and depletion of the available natural resources. It is important to note that consumers are involved in environmentally conscious consumption because they have acknowledged personal responsibility for the environmental pollution problem (Hoyer, 2008). The influence on consumers to adopt the approach of environmentally friendly consumption has been enhanced by media campaigns organized by various stakeholders in collaboration with relevant government institutions. Producing and supplying environmentally friendly products is one of the effective selling points for most corporations all over the world. This paper will therefore discuss ways in which property development companies can target and then position themselves into the growing market arising from Environmentally Conscious Consumer Behavior in Malaysia. How property development companies can target and then, position themselves into the growing market arising from the ECCB in Malaysia Producing eco-friendly products is one of the most important promotional points for the 21st century corporations. This is facilitated by the fact that most product consumers in Malaysia are increasingly becoming aware of the need to conserve the environment, especially with respect to climate change; and the trend is the same all over the world. Consequently, this has resulted into a market where consumers are more drawn to environmentally friendly products than ever. Going by the statistics provided by the United Nations Environmental Programme (2007) property developments industry contributes approximately 30%-40% of the total global carbon dioxide emission arising from energy consumption. Coupled with the market arising from Environmentally Conscious Consumer Behavior, the property development sector is forced to reconsider the products it avails to the consumers in the property market. There are arrange of options available to the property developers in Malaysia that can enable them to target and position themselves in the Malaysian market arising from Environmentally Conscious Consumer Behavior. It is important to note that consumers are increasingly becoming concerned about global warming and one way through which they can effective participate is by holding producers accountable to global warming paying attention to whether the production process leads to increased greenhouse gas emissions (Fischer & Black, 1995). One of the ways through which the property development companies in Malaysia can use to target and position themselves in Malaysian market is reducing energy usage for the property in offer. The companies can ensure the lighting systems in their property utilize more environmental friendly energy sources. For instance, they can face out the use of traditional incandescent bulbs and replace them with compact fluorescent lighting tubes (Kelly, 2009). It is also crucial to note that a larger percentage of energy consumptions take place during the period buildings are in use than during the construction process. The energy usage during the life time of a building, energy usage may include heating, ventilation, cooling and lighting amongst other energy using appliances. In order to target and position themselves in the Malaysian property market, the companies can adopt the use of the most advanced technologies like thermal insulation, utilize solar shading and also fit their property with energy efficient appliances (Kelly, 2009). The Standards and Industrial Research Institute of Malaysia (SIRIM) came up with a labeling program in which products are verified as environmentally friendly. The property companies ensure that they purchase their fittings from such suppliers whose products are genuinely labeled as environment friendly; this should be informed by the fact that as many of Malaysian consumers as possible are becoming aware of the labeling programme and hence are cautious with their consumption behavior. Besides, this can be reinforced by engaging more in environmental campaigns to convince the consumers that they seriously committed to the conservation of environment and its resources (Abdullah, 1999). The materials used in constructing property are very crucial in terms of environmental concerns. The property companies should use non-toxic construction materials that do not contain chemicals and substances like mercury and the in the process of marketing they should emphasize on such characteristics. Moreover, it is important to note that environment conservation groups are slowly increasing in number; these groups have attracted the attention of the advertising firms. It is of great benefit for property companies in Malaysia to use these groups and or advertise through the firms that have strong link with such groups (Wells, 2007). Disposal of household wastes are an important component of environmental conservation. Property companies should ensure that their buildings are equipped with safe, efficient and eco-friendly means of disposing wastes. This may include mobile waste bins which can be emptied in a track and waste transported to appropriate places. In addition to this, the sewerage systems should also encourage hygiene and have no health risks which are some of the major concerns for most consumers (Snyder, 2000). There are also a number of activities that companies can initiate and support amongst the Malaysian communities. They can fund eco-friendly initiatives like planting of trees and facilitating research towards finding alternative energy sources. Again, the companies can ensure that their property is located in a clean neighborhood. This has the potential to attract more of the Environmentally Conscious Consumers (ECC). Conclusion Environmentally Conscious Consumer Behavior has had significant effects on how property companies strategize on penetrating the market. The companies have to ensure their products are environmentally friendly so as to attract the Malaysian property buyers. However, there are range strategies that can assist the companies in targeting and positioning themselves in the Malaysian property market where consumers are increasing getting concerned with the conservation of environment. When the buildings are constructed with harmless materials which do not contain chemicals and substances like mercury, the companies are highly likely to get more buyers. Moreover, with label identity policy for eco-friendly products in Malaysia, most consumers will check on such labels before finally making purchase. It is therefore imperative that property companies should partner with such suppliers whose products meet the labeling standards (Abdullah, 1999). The companies can also ensure that lighting systems in their property are energy efficient. Instead of using the traditional lighting bulbs like incandescent, the companies can fit their buildings with energy efficient fluorescent tubes (Kelly, 2009). Besides, they can also support environment conservation initiatives in communities; this can also include using advertising firms that have strong links with environment conservation groups. References Abdullah, M. (1999). Small and medium enterprises in Malaysia: policy issues and challenges. Malaysia: Ashgate. Fischer, F. & Black, M. (1995). Greening environmental policy: the politics of a sustainable future. United States: Palgrave Macmillan. Hoyer, D. , et al. (2008). Consumer Behavior. London: Cengage Learning. Kelly, D. (2009). Community planning: an introduction to the comprehensive plan. U. S: Island Press. Rauschelbach, B. (2002). Cooperating for sustainable tourism: proceedings of the Forum International at the Reisepavillon, 2002. U. S: Kasparek Verlag. Snyder, C. (2000). Union County, Pennsylvania: a celebration of history. U. S: Penn State Press. United Ntaions Environmental Programme. (March 2007). Environment for development. Retrieved from: http://www. unep. org/Documents. Multilingual/Default. asp? DocumentID=502&ArticleID=5545&l=en[Accessed August 24, 2010]. Wells, W. (2007). Blueprint for greening affordable housing. United States: Island Press. Woolley, T. & Kimmins, S. (2000). Green building handbook: a guide to building products and their impact on the environment, Volume 2. New York: Taylor & Francis.

Compare the Opening and Closing Scenes in Of Mice and Men Essay

Of mice and men is a great novel written by protest writer John Steinbeck. It is a sad story about the life of two migrant ranch workers George and Lennie, and the conflicts between the reality and their relationship and dream. The opening and closing scenes are both set in the same place – Salinas River, however readers can sense totally different feelings from these two scenes. In this essay I am going to compare the opening and closing scenes of this novel focus on the following points: 1) the description of nature to evoke feelings, 2) The dialogue, and the way George and Lennie speak to each other, to explore how George change towards Lennie, 3) The dream George and Lennie share, to explore how Steinbeck protests against the reality. The opening scene in of Mice and Men is happy and peaceful compared to the closing scenes. Before the entry of the two main characters, Steinbeck gets the audience involved by describing the idyllic setting: the beautiful, colorful, peaceful and poetic evening in Salinas River. He creates the pleasant atmosphere brilliantly by sensational words like ‘deep and green’ water, ‘yellow sand’, ‘golden foothill slopes’, ‘fresh and green’ willows, ‘mottled’ sycamores. Just like a strong warm visual effect colorful oil-painting, the Willow Pool in Salinas River vividly present to us. It is also a calm peaceful riverside, little creatures like lizard, rabbit, coon, dears, heron are freely and actively wondering on the riverside. The feeling of relaxation in a warm afternoon is evoked and emphasized in depicting. â€Å"The water is warm too, for it has slipped twinkling over the yellow sands†; â€Å"†¦the leaves lie d eep and so crisp that a lizard makes a great skittering if he runs among them†¦.† This untainted beauty of the nature and the relaxed serenity atmosphere that Steinbeck wisely opens with tending toward the Romantic. It suggests a purity and perfection sense–>sense of purity to the reader that associates with the innocence of Lennie; indicates the idealized friendship and the romanticized dream between George and Lennie. On the other hand it helps to emphasize the changing atmosphere when two protagonists enter into the scene. By comparison to the same scene in the closing ending–scene it hints about the future trouble and the calm before the storm. The setting is also a symbol of a place free from society, a safe sanctuary for Lennie and George, where they can be themselves. That’s why George chooses to let Lennie come back here when he meets trouble, and even Lennie is finally killed by George in mercy here, the Salinas River does keep Lennie safe from the torture of being killed curly. The description of the landscape also helps us to develop an understanding of the background of the great depression. â€Å"There is a path through the willows and among the †¦ sycamores, a path beaten hard by boys†¦., and beaten hard by tramps †¦.† â€Å"†¦the limb is worm smooth by men who have sat on it.† Boys working in the ranch swim here and tramps traveling pass here trying to get job, use it as a rest area. It shows the background of great depression, people struggle with financial freedom, they had to drift into the country for jobs in the farming industry. The ending of the novel occurs at the exactly same place where the story started. The landscape is still the same; however they suggest a totally different feeling. â€Å"Already the sun had left the valley†; â€Å"by the pool among the mottled sycamores, a pleasant shade had fallen†. The sunset is normally symbolic the end of life, it is a subtle foreboding–indication of the impending death of Lennie. The changing landscape in the coming evening is also described in the other three plots. All these plots are following by the description of the chasing people coming nearer. Steinbeck uses the description of setting as an important tool to convey that Lennie’s death is impending. Readers can also notice that the peaceful and untainted atmosphere is replaced by violent – a heron ate a snake and waiting for another. The scene is not anymore slow and relaxed; instead â€Å"A far rush of wind sounded and a gust drove through the tops of the trees like a wave.† Dry leaves â€Å"scudded a few feet†; Things become swift and dramatic; they are signifying the turmoil George and Lennie have and are going to suffer. Apart from using the setting to underline the themes, Steinbeck is also accomplished–excelled in using creatures and their imagery to illustrate the themes and suggest the foreboding on what George and Lennie will suffer. In the opening chapter, as the human footsteps approached, the rabbits â€Å"hurried noiselessly for cover†; the heron â€Å"labored up† and â€Å"pound down river†. â€Å"For a moment the place was lifeless†. Creatures like lizards, rabbits, herons, coons, deers are in possession of the peaceful land, however when human being invaded, we can suddenly sense the tension in this scene — the dangers can lurk–appear at every turn, weak creatures can become prey anytime. They are good indications of a predatory world that George and Lennie are in. In the closing chapter, Steinbeck reflects some animals in the first section. He vividly describes the cold, deliberate way a large heron killed a water snake. The unsuspected snake â€Å"glided smoothly up the pool†, it is totally unaware that â€Å"in the shallows† there is a heron stood â€Å"motionless† waiting for it. â€Å"A silent head and beak lanced down and plucked it out by the head, and the beak swallowed the little snake while its tail waved frantically†. Death of the helpless water snake comes so quickly, surely, and to the unaware. Normally, snake is a symbol of evil, however here it is utter–>completely helpless, and it is eaten by a heron, which is commonly regarded as a sign of goodness. This dramatic scene implies the helpless and unsuspecting Lennie who will be killed by his best friend -George, who is as cool as the heron (the situation forced George to shoot Lennie quickly). George killed Lennie with mercy, because he knows at least Lennie will die with happiness and without fear like the unaware snake. In the opening chapter of Of Mice and Men, Steinbeck solidly established the character profile for George and Lennie, as well as their relationship. Apart from the description of their physical characteristics, Steinbeck achieves this heavy reliance on the great proportion of direct speech dialogue between George and Lennie. The language that George and Lennie used in their conversation is fairly simple and contains commonly used American slang like â€Å"brang†, â€Å"would of†, â€Å"gonna†, â€Å"kinda† â€Å"for a sack†, etc. This help to reflect the setting and their down-to-earth uneducated ranch worker’s lifestyle and make an authentic–>real sense. The relationship between George and Lennie is clearly established right from the beginning of the book when George sternly warns Lennie to stop drinking water from the pool. â€Å"Lennie, for God’s sake don’t drink so much'†; â€Å"You gonna be sick like you w last night.† â€Å"‘you never oughta drink water when it ain’t running†. George said these â€Å"sharply† and â€Å"hopelessly†. Readers can soon perceive–>feel that George is clearly a leader and guardian who guides and protects Lennie. He looks out for Lennie’s safety and instructs him on what to do. He talks to Lennie in a patronizing but a caring way. Whereas, Lennie is a big, half-wit, child-minded person, who is also sweet and loving. â€Å"That’s good,† he said. â€Å"You drink some, George. You take a good big drink† â€Å"Look, George. Look what I done† Just like an innocent child, Lennie enjoys the pure pleasure by drinking and playing the water, and his first thought is to share the pleasure with George. With the plot progression, we got clearer that George is a small but clever, level-headed man. He loves Lennie, takes care of Lennie, guides Lennie, and protects Lennie like a father. He looks after all Lennie’s affairs, even carrying Lennie’s work card for him. He also always bails–bail Lennie out of the trouble, or even potential trouble, as he knows Lennie can get himself into trouble very easily. George instructs Lennie â€Å"Get into the brush till I come for you† if Lennie gets into any trouble. Meanwhile, although George is Lennie’s mentor–guardian, he also looks up to Lennie’s feeling, respects his behavior with understanding even though sometimes it seems odd. When George found a dead mouse, he takes the dead mouse away from Lennie. This hurts Lennie’ feeling and he starts to whimper. George â€Å"put his hand on Lennie’s shoulder† to comfort him. He did this for Lennie’s good. â€Å"I ain’t takin’ it away jus’ for meanness†. That mouse ain’t fresh†¦.you get another mouse that’s fresh and I’ll let you keep it a while†. He promises Lennie to give a pup for Lennie to pet. â€Å"First chance I get I’ll give you a pup,†¦That’d be better than mice. And you could pet it harder.† He even plans a future with Lennie, â€Å"..we’re gonna get the jack together and we’re gonna have a little house and a couple of acres †¦.† George is also a short-tempered person, he often gets irritated, weary, frustrated with the difficulties of his responsibility for taking care of Lennie, such as Lennie’s forgetfulness. When Lennie forgot where they are heading to, George swears and scolds in anger: â€Å"So you forgot that awready, did you? I gotta tell you again, do I? Jesus Christ, you’re a crazy bastard!† â€Å"The hell with the rabbits. That’s all you ever can remember is them rabbits. Of Mice and Men.K. Now you listen†¦.† The way George treat Lennie is just like the way an overtaxed–frustrated parent treats a little boy. Lennie asks for ketchup childishly during the dinner. This innocent request sparkle–sparkles George’s frustration again. He â€Å"exploded† his voiced â€Å"furiously†, and â€Å"rose nearly to a shout†. He launches a long complaining speech about the difficulties that Lennie brought to him; states that without caring for Lennie he can live a far easier life. In anger George declares† If I was alone I could live so easy. I could go get a job an’ work, an’ no trouble. No mess at all†¦.† On the other hand, despite George’s harsh, derogatory responses, Lennie never gets annoyed. Because–because Lennie looks up to George as an idol, he mimics action of George’s. He loves George and treats him as the most important person in his life. Each time when Lennie realizes he has done something wrong, he always try to please George and quell–calm his anger, because he is afraid George will leave him. â€Å"Lennie knelt and looked over the fire at the angry George. And Lennie’s face was drawn with terror.† â€Å"George† very softly â€Å"I was only foolin’, George. I don’t want no ketchup. I wouldn’t eat no ketchup if it was right here beside me.† When George said if they got ketchup, Lennie can have some, Lennie said â€Å"I’d leave it all for you†¦and I wouldn’t touch none of it.† He even suggests he can leave George alone and go live in a cave. Although Lennie is half-witted, he has enough sense to know that George loves him, so he plays with George’s guilty conscience, and sympathy for George to ask him to stay with him. As expected, George feels guilt to his friend as early as when he sees Lennie’s â€Å"anguished face†. â€Å"I been mean, ain’t I?† he said to Lennie â€Å"I want you to stay with me, Lennie. Jesus Christ, somebody’d shoot you for a coyote if you was by yourself†¦..Your Aunt Clara wouldn’t like you running off by yourself,†¦.† George knows clearly without him his dim-witted friend Lennie cannot survive by his own. Also as a promise to Lennie’s Aunt, George feels responsible to look after Lennie. After Lennie is assured that George will not leave him, he pleads George to recite their familiar dream. On the thought of their dream, George’s voice turns to â€Å"deeper† and â€Å"rhythmically†. It is very contagious, as a reader–readers we are immediately drawn in by the dream, which is just as beautiful as the landscape that Steinbeck describes in the open setting — free and idyllic. â€Å"Guys like us, that work on ranches, are the loneliest guys in the world†¦.They ain’t got nothing to look ahead to.† â€Å"With us it ain’t like that. We got a future. We got somebody to talk to that gives a damn about us. We don’t have to†¦..But not us.† These important quotes further highlights to us that George is actually a royal, loving, devoted friend rather than father, brother or guidance. Because he is so willing to admit that he appreciates Lennie’s companionship, because he needs Lennie emotionally, they rely on and look after each other. Also he knows it is the companionship and the special strong bond they share that set them apart from other homeless lonely ranch workers,their friendship make a strong support during the hardships and predicaments in the special era. Despite his annoyance, George stays with Lennie by a combination of the motivations of pity, responsibility and gets a company in the hard time. It is these facts that propel–push George to stay loyal to Lennie and devotes Lennie through thick and thin. In the closing chapter, readers can soon notice the way George and Lennie talk to each other changes. † ‘What the hell you yellin’ about?'†. When George sees Lennie again in the pool, he still swears, however it is his only way to talk. He turns a lot quieter this time. He is softer to Lennie, without scolding or blaming like before. When he repeats the life he yearns for followed by Lennie’s request, his tone is â€Å"woodenly† and â€Å"monotonous†, with â€Å"no emphasis†. By contrast, in the opening chapter, his long speech with same content was emotionally rich and lyrical. When George recounts the dream to Lennie again before he shoots Lennie, he struggles to maintain his co mposure and optimism, as at that moment his heart is in despair. However he did try to give Lennie a hope that their dream is achievable and will fulfill soon. â€Å"Ever’body gonna be nice to you. Ain’t gonna be no more trouble. Nobbody gonna hurt nobody nor steal from’ em.† â€Å"Look acrost the river, Lennie, an’ I’ll tell you so you can almost see it†. Right before George kills Lennie in mercy, George declares: â€Å"no, Lennie. I ain’t mad. I never been mad, an’ I ain’t now. That’s a thing I want ya to know.† This is the finally words George talk to Lennie, in this sentence; we can sense how loving and devoted George is to his friend Lennie. Lennie talks to George with great sense of guilt and intense fear. As he knows he has done another very bad thing. He is still unaware of the bad fate that facing him. What he is afraid of is George will disapprove and leave him this time. He knows every time when he causes trouble, George will complain about his burden, and threaten to leave him. He then plays the trick again to gain sympathy and make sure George won’t leave him. Different with before, this time George didn’t get irritated, and assure Lennie that he won’t leave. â€Å"I knowed it† Lennie cried. â€Å"You ain’t that kind†. Lennie still holds the childlike faith that George will always be there for him. This assured faith relieves him a lot. Same as the opening in the novel, Lennie further requests George to repeat the dream again, because the dream gives both him and George comfort. George never wants Lennie to be hurt, but in the end he realizes that he is out of options to protect Lennie, the death of Lennie is inevitable–unavoidable. In order to protect Lennie from suffering tortures in a painful death. George is forced to shoot Lennie while Lennie is occupied with their shared dream of the farm, which is his favorite story and always soothes and comforts him. With the respect, love and responsibility towards Lennie, George has chosen the best option in the situation, and gives Lennie the best gift he can, the gift of peace, which can save Lennie from a hellish life in a forever asylum-dreadful life. One of the main themes in Of Mice and Men is American dreams. During the Great Depression the harsh realities make people lonely and powerless and hopeless, to share a dream of a better place is the only outlet to comfort them and help to transcend–from the troubles they face. Steinbeck introduces this dream for George and Lennie in the very first chapter. â€Å"With us it ain’t like that. We got a future.†- Despite the hard and gruff reality, George is still an idealist and self-motivated man at the beginning of the novel. He believes through their hard working, his dream of â€Å"live off the fatta the lan† can be achievable , and there is something better up ahead, as he got Lennie. It is Lennie and their strong bond that keep them from the terrible isolation that the other men experience, and gives George a special sense of purpose to strive for. Their friendship sustains their dream and makes it possible. However, with a world filled with harsh adversity and predatory–circumstances, their relationship just can’t simply sustain. George and Lennie are forced to separate tragically. By killing Lennie, George is also forced to shoot his dream, forced to surrender his faith of the Land of Promise. Without Lennie, George is now in loneness and hopelessness, just the same as anyone among the legion of poor, homeless, powerless migrant workers. The tragedy for them is, no matter how hard they work they are doomed–fated to a life of wandering, no matter how intensely they dream, their dreams can only help transcend their circumstances, but no way to be fulfilled. The faded American dream in the closing chapter sadly shows that a land of freedom, contentment, and safety is not possible to be found in this world, it is only an Eden-like place. Actually, at the end of the opening chapter, when Steinbeck deliberately wrote on the rabbit with different colors which Lennie desired is already a hint of the unrealistic fantasy of George and Lennie. Through the comparison of the opening and ending scenes in Of Mice and Men, we can find that the settings are very important in these two parts, Steinbeck used them to help evoke different feelings and hint about the future troubles, as well as symbolize the main themes. Dialogues between George and Lennie are the main content of these two scenes, they help to characterize the main roles and establish and develop the main themes – loneliness, friendship, and dream. Through these main themes Steinbeck portrayed the hardship that ranch workers like George and Lennie encountered during the heartbreaking Depression era. He has succeeded in describing the cruelty and insurmountable -extremely difficult challenges during the Depression.

Leadership and Teamwork in Management Essay Example | Topics and Well Written Essays - 3000 words

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History of Photography Research Paper Example | Topics and Well Written Essays - 1750 words

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